A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling
Breast cancer remains a major health problem worldwide.While chemotherapy represents an important therapeutic modality against breast cancer, limitations in the clinical use of chemotherapy remain formidable because of chemoresistance.The HER2/PI-3K/Akt pathway has been demonstrated to play a causal role in conferring a broad chemoresistance in bre